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Do not increase your dose or use this drug more often or for longer than prescribedYour condition will not improve any fasterand your risk of serious side effects will increase.
Verify the pregnancy status of females of reproductive potential prior to initiating HYDREA therapy.
Monitor blood counts at least once a week during HYDREA therapySevere anemia must be corrected before initiating therapy with HYDREAConsider dose modifications for other toxicities.
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in long term use of hydrea, secondary leukaemia has been reported.