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Information about Xeloda.
UsesXeloda often is used in combination with other anticancer medicinesTypically it’s used to treat metastatic breast cancer that has stopped responding to TaxolTaxotereand Adriamycin.
Other than warfarinno formal drug-drug interaction studies between XELODA and other CYP2C9 substrates have been conductedCare should be exercised when XELODA is coadministered with CYP2C9 substrates.
MonotherapyMetastatic Colorectal CancerAdjuvant Colorectal CancerMetastatic Breast Cancer)
The efficacy endpoints for the two phase 3 trials are shown in Table 14 and Table 15.
Based on postmarketing reportspatients with certain homozygous or certain compound heterozygous mutations in the DPD gene that result in complete or near complete absence of DPD activity are at increased risk for acute early-onset of toxicity and severelife-threateningor fatal adverse reactions caused by XELODAe.gmucositisdiarrheaneutropeniaand neurotoxicityPatients with partial DPD activity may also have increased risk of severelife-threateningor fatal adverse reactions caused by XELODA.
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in a week, if he has healed the doctor will have him resume the xeloda treatment but reduce the dosage down from the current 4000mg.
