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Because fluoxetine is tightly bound to plasma proteinsadverse effects may result from displacement of protein-bound fluoxetine by other tightly bound drugssee CLINICAL PHARMACOLOGY

In the tables and tabulations that followCOSTART Dictionary terminology has been used to classify reported adverse reactionsThe stated frequencies represent the proportion of individuals who experiencedat least oncea treatment-emergent adverse reaction of the type listedA reaction was considered treatment-emergent if it occurred for the first time or worsened while receiving therapy following baseline evaluationIt is important to emphasize that reactions reported during therapy were not necessarily caused by it.

Nauseadrowsinessdizzinessanxietytrouble sleepingloss of appetitetirednesssweatingor yawning may occurIf any of these effects persist or worsentell your doctor promptly.

Anxietynervousnessand insomnia were associated with discontinuation for SARAFEMsee Table 4 and Discontinuation of Treatment

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but with the help of what taylor nelson sofres cmr pegged as a 14 million-plus direct-to-consumer ad effort in only a period of months, sarafem generated some 33 million in sales in the five months it was available in 2000, according to ndc health.

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