The most commonly prescribed antiemetic drugs are the phenothiazines including prochlorperazine and thiethylperazine or antihistamine agents including promethazine .
Information about Promethazine.
Do not let anyone else take your medicationAsk your pharmacist any questions you have about refilling your prescription.
Medicines to treat Parkinson’s diseaserestless leg syndromeor pituitary gland tumorprolactinomaor.
Allergic rhinitisrunny nose and watery eyesAllergic conjunctivitisredwatery eyesAllergic skin reactionsrashhivesAllergic reactions to blood or plasma products.
The FDA advised manufacturers to include in the black box warning that the preferred route of intravenous administration is deep intramuscular injectiondirectly into a muscleand not subcutaneous injectioninto the layer of skin directly below the dermis and epidermis
CNS DepressantsPromethazine hydrochloride tablets may increaseprolongor intensify the sedative action of other central-nervous-system depressantssuch as alcoholsedatives/hypnoticsincluding barbituratesnarcoticsnarcotic analgesicsgeneral anestheticstricyclic anti-depressantsand tranquilizersthereforesuch agents should be avoided or administered in reduced dosage to patients receiving promethazine HClWhen given concomitantly with promethazine hydrochloride tabletsthe dose of barbiturates should be reduced by at least one-halfand the dose of narcotics should be reduced by one-quarter to one-halfDosage must be individualizedExcessive amounts of promethazine HClpromethazine hydrochloriderelative to a narcotic may lead to restlessness and motor hyperactivity in the patient with painthese symptoms usually disappear with adequate control of the pain.
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